Showing posts with label hairloss. Show all posts
Showing posts with label hairloss. Show all posts

Saturday, April 25, 2009

Baldness: Resveratrol & Curcumin Grow Hair

I have been taking resveratrol for hair loss for months and I've noticed great things about my skin but not so much my hair growth. I remembered seeing the 60 minutes story featuring resveratrol and remembered that it needed to be mixed with Curcumin to help stop hair loss.

Here is the study regarding Resveratrol and Curcumin for Hair loss. It is everywhere online but I wanted to post it for my readers. I have researched the best Resveratrol and Curcumin to buy because every one and their mother is selling watered down versions of resvertrol which don't even seem to come from the right natural source.

I'm not selling anything on this site so if you want to know what I use and how I get it at a reduced cost through smart shopping, just leave me a comment. I really just want people to get hair loss and hair loss remedy info on my blog. Not sales, sales, sales!

PHARMACEUTICAL COMPOSITION COMPRISING CURCUMIN AND RESVERATROL AND USES THEREOF IN MEDICAL FIELD
The present invention deals with a pharmaceutical composition comprising curcumin and resveratrol and uses thereof in medical field. More specifically, the composition object of the invention can be advantageously employed for retarding ageing, for the prevention of vascular diseases, for the treatment and prevention of cancers as, for example, prostate carcinoma, skin diseases as psoriasis, and diseases of the piliferous system as hair loss.
Resveratrol is a polyphenol present in grapes, especially in its peel and in its seeds.
Curcumin is an extract of the root of the Curcumea Longa, a plant well known since a long time for its pharmaceutical properties. Nowadays curcumin is well known for its power of reducing cholesterol, its diuretic, choleretic, anti-inflammatory ability and for ameliorating the general conditions of patients treated with chemotherapy for neoplasia.
Particular feature of Curcumin is to belong to the capsaicinoids family, substances characterized by a pungent taste, similar to the one of pepper. From a point of view of molecular biology, the presence of a vanilloid receptor on the cell membrane and close to the mitochondrial structures can explain the induction of apoptosis or planned death of cells that would have become neoplastic. Moreover, in the Central Nervous System there are various receptors of capsaicinoids and this could explain the enhancement of the anti-aging action of resveratrol by curcumin.
The group of patients that has assumed only resveratrol didn't show any modification on the PSA, while the group treated with resveratrol and curcumin showed with great surprise a reduction, sometimes also relevant, in variable time periods. Moreover, during this testing, the patients treated with resveratrol and curcumin surprisingly showed positive improvements in the treatment of psoriasis and the attenuation and even a stop of the hair loss, a reduction of the hair graying and the rebirth of hair in bald areas sometimes even of the original color too.
Regarding its action on hair growth, even if not yet known, it is probably linked to the release of P substance. The growth and the pigmentation of the hair follicle would depend on mesenchymal-epithelium-neiroderic interactions not very well-known yet, where the P substance would stimulate the hair growth in vivo (RaIf Paus et al Investigation Labs, VoI 71, No 1 , p.135, 1994).
According to the invention, the pharmaceutical composition can comprise also vitamin E and/or wheat germs containing vitamin E. In fact, the powdered wheat germs are one of the richest natural resources of vitamin E (or tocopherol) and are one of the most effective antioxidants against free radicals, the aggressive substances that proliferate in our body because of the action of pollution, inaccurate diets, sun or just age.
According to another embodiment of the present invention, the pharmaceutical composition can also comprise Capsaicin and/or the fruit of capsicum annum, which contains capsaicin. Capsicum annum, its powdered fruit in particular, is rich in important nutritional substances as flavonoids, vitamins (C, E, PP, and K), lecithins, mineral salts and capsaicin, an alkaloid responsible for its particular taste and for its activating properties. The extract of capsicum seems to be very effective in stimulating the vitality of the tissues and in activating the venous and capillary circulation.
In particular, in the composition according to this invention, the content of resveratrol can range from 3 to 6 mg; of Curcumin from 15 to 30 mg; of vitamin E from 50 to 100 mg; of vitamin C from 10 to 30 mg; of capsaicin from 2 to 5 mg; of powdered wheat germs from 50 to 450 mg.
The composition according to the invention can be presented in capsules, pills, solution and emulsion. If in capsules or pills, the suggested dosage is one or two units, before meals.
Further object of the present invention is the use of the composition for the cancer treatment, in particular the treatment of prostate carcinoma. Moreover, the composition according to the invention can be advantageously employed for the treatment of skin diseases, in particular of psoriasis, for the treatment and the prevention from ageing, for the treatment and the prophylaxis of diseases .of the piliferous system, in particular of alopecia.
Another object of the present invention is a combination comprising resveratrol and curcumin for the simultaneous, separate or sequential use in the treatment of cancer, as for example, the prostate carcinoma, in the treatment of skin diseases as psoriasis and for the prevention and the treatment of alopecia.
The invention in fact can vary in its dosages and in its components, adding other components similar to the one suggested, but without altering the conceptual basis of the invention.
In this testing, apart from a relevant anti-cancer action on hormone-insensible prostate neoplasia, an effect on some patients has also been the stop of the hair loss and the growth of hair, sometimes of the original color too. Therefore patients without any neoplastic disease, but affected by alopecia or hair loss, have been included to the testing.
MATERIALS AND METHODS
The group treated only with resveratrol didn't show any relevant variation, except from two cases that showed a slight decrease.
Capsures of 4 pills a day let to a reduction in the level of PSA after 60 days to 7.4 and then to 6.80. The patient suffered also of psoriasis of the scalp, that disappeared after the treatment and that by now, after 8 months has not reappeared. Case 6: 64 years old man affected by prostratitis that tried various treatments. After the treatment with Capsures, 6 capsules a day, after 30 days had no more perineal pain and had a hair growth.
Case 14: 75 years old man, operated 4 years before for radical prostatectomy, intolerant to hormonal treatment he has been treated with Capsures, 4 pills a day for 60 days. His PSA value reduced from 4.5 to 2.4.
As far as its action on hair is concerned, some patients, especially women that were considerably loosing their hair, after 20 days of treatment confirmed to have had a reduction in their hair loss. In bald patients, the hair, sometimes of the original color restarted to grow even after the ablation of the white hair.
CONSIDERATIONS AND CONCLUSIONS
The compound containing just resveratrol as active agent (Resverage) didn't cause a reduction of the PSA value and this can be due to the low bioavailability of the molecule. In the cases of prostate carcinoma the efficacy of the association of resveratrol with curcumin can be due to a higher concentration in the circulation and therefore in the tissues explained by the lipophilia of the active elements of curcumin.
The association of resveratrol and curcumin seems to have a synergic effect that enhances the anti-inflammatory power of the two active elements. It is an essential activity because in the prostate carcinoma there is a phlogistic action caused by hyperincretion of enzymes as the cyclooxygenase 1 and 2.
As far as the action on hair is concerned, it is unquestionably due to the administration of the two combined active elements, since in the compound with just resveratrol no result has been shown and in the many cases in India and in Europe where Curcumin has been employed, any effect on hair has never been reported. The most important aspect rarely highlighted is that curcuminoids are capsaicinoid substances.
Those fibers, whose nerve cell is in the posterior roots, once stimulated release neuropeptides like the P substance, Neurokinin A and the Calcitonin Gene Related Peptide (CGRP). Experimental researches demonstrated that the desensibilization of those fibers leads to skin lesions localized in the cervical region of the rat. These experiments indicate the existence of a tropic function. It is probable that the loss of hair is a result of the deficit of neuropeptides released by the fibers that innervate the scalp.
Therefore it is possible that the administration of a substance that has as activity similar to capsaicin, as the Curcumin that metabolizes like an active curcumoid, can stimulate the sensorial fibers that have a tropic function, and that resveratrol has a vehicular function on the tissues. Therefore, the composition of the present invention is active on cases of hormone-insensible prostate carcinoma but in particular on hair, as our research has proven. The efficacy of the composition according to the present invention also depends on the great lyophilic properties of a capsaicinoid, curcumin on the anti-inflammatory effect of the two substances.
The interference of the hormonal action on hair loss is unquestionable, even if capsaicinoid-sensible sensory innervations are an ancestral phenomenon that does not depend on the hormonal mechanisms, but through a metabolic way different from the ordinary one. The growth and the pigmentation of the hair follicle seem to be controlled by epitelius-mesenchimoneuroechtodermmic interactions not very well known, but with an important role of the P substance on the hair growth in vivo.

Saturday, April 18, 2009

Resveratrol and Curcumin For Hairloss

All the news about Resveratrol and hair loss has gotten me pretty excited but as always when it comes to growing hair and baldness cures I have high hope and low expectations.

I will say that in a lot of these hair loss forums there's a lot of buzz about how Curcumin enhances the effects of Resveratrol so of course, I'm getting in on this one.

About 2 months ago went to the health food store and bought some curcumin and a bottle of resveratrol but I didn't really know what I was doing.

So after a bit of research I've gotten some of what is considered the best of the best and gone with

Jarrow Formulas Resveratrol 100 and take Life Extension Super Bio-Curcumin

Now this is just part of my regiment that is producing those exicting little buds of new hair growth but I'm going to take this stuff until the science says its bunk.

By the way, the links above are about 40% cheaper than buying it at a store. If you include the following promo code LAT159 , you will recieve $5 of your order and accumulate credit for each purchase you make from I-herb

Taking supplements can get expensive so finding a place to buy vitamins online is great.

Sunday, April 12, 2009

Rogaine on Steroid to Stop Hair Loss

Minoxidil and Hair Growth

You know years ago I glopped a bunch of Rogaine on my head to try and grow some peach fuzz on the top of my head because the FDA said I could.

Now anyone suffering from male pattern baldness or female hair loss isn't looking for peach fuzz. We want hair and Rogaine typically was not the answer.

However, these days, every doctor and mad scientist is screwing around with minoxidil to make it better, faster and stronger and some of these brews will help you stop hair from falling out.

Which Minoxidil Formula Will Work Best?

Using Minoxidil topically to grow hair was discovered by chance. Minoxidil was originally developed to treat hypertension, but patients taking Minoxidil started growing unwanted hair. This side effect led to the testing of using topical Minoxidil to grow hair on balding sites.

Both males and females may use generic Minoxidil. Generic Minoxidil comes in two concentrations, mainly 2% and 5%. It is recommended that males use Generic Minoxidil 5% whilst females use Generic Minoxidil 2%.

Minoxidil works best on the crown. Why Minoxidil works remains a mystery. Generic Minoxidil is a vasodilator and may increase the blood supply to the follicles. Minoxidil has to be applied twice a day to the affected area for at lest six months. Since it is applied locally, Generic Minoxidil is relatively safe as negligible amounts are absorbed in the bloodstream.

There are now so many variations of Minoxidil out there that choosing the right one is nearly impossible because everyone is trying to sell you something. The important part is to use one of them because even though it will probably not help grow your hair back it will slow the hairloss down.


I try to keep it simple: I use Rogaine 5% because it is readily available and inexpensive. Then I put a few drops of rosemary oil and liquid saw palmetto extract in as well. Rosemary has long been associated with hair health and saw palmetto is a natural DHT blocker used by many hair loss sufferers. All of these items can be found at

Saturday, April 11, 2009

Dutasteride Really Does Work to Stop Hairloss


Stop Your Hair Loss

Dutasteride is the active ingredient in Avodart which is used in the treatment for an enlarged prostate. It blocks DHT which is a major factor in Male Pattern Baldness. It is not prescribed for hair loss but if you are a hairloss freak like me you may want to get a hold of some.

Now, since it is a prescription drug I am not going to tell you where to get it without a perscription. I get it and I use it. I have had no side effects whatesover and I will continue to use it forever or until something better comes along. I'm sorry I cannot help you contact the Dustasteride Discount Pharmacy but if there are no advertisers selling discount generic dutas, proprecia and proscar from discount pharmacies on other pages, just leave a comment and I will help you out if I can. send you to an
Contact the Dutasteride Discount Pharmacy
off shore pharmacy that will sell it to you without a perscription but if you are smart you will be able to find some on this page. I'm sure there are ads for it somehwere.

Before you deside to self diagnose your hairloss problems, please now that propecia does work a little bit. It laymens terms it stops one type of DHT from forming and that helps allot with keeping your hear.

Dutasteride, dutas, avodart and generic avodart inhibits two types of DHT from effecting the scalp so it is better. It will probably be approved by the FDA in some form or another down the road but it is used all over the world to treat hair loss.

Again, if you search hair loss forums around the web you will find stories from hundreds of men using dutas for mail pattern baldness and very few will report bad side effects.

So let's learn a little more about Dutasteride


Dutasteride (marketed as Avodart, Avidart, Avolve, Duagen, Dutas, Dutagen, Duprost) is a 5-alpha-reductase inhibitor5-alpha-reductase inhibitor, a drug which inhibits the conversion of testosterone into dihydrotestosterone (DHT). It is used to treat conditions caused by DHT, such as benign prostatic hyperplasia (BPH). Avodart is manufactured and marketed by GlaxoSmithKline.

Dutasteride belongs to a class of drugs called 5-alpha-reductase inhibitors, which block the action of the 5-alpha-reductase enzymes that convert testosterone into dihydrotestosterone (DHT). Finasteride also belongs to this group. Dutasteride inhibits both isoforms of 5-alpha reductase, while finasteride inhibits only one. But a clinical study done by GlaxoSmithKline, the EPICS trial, did not find dutasteride to be more effective than finasteride in treating BPH.

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trial of another drug and may not reflect the rates observed in practice.

The most common adverse reactions reported in subjects receiving AVODART were impotence, decreased libido, breast disorders (including "Gynecomastia" Ejaculation disorders. Study withdrawal due to adverse reactions occurred in 4% of subjects receiving AVODART and 3% of subjects receiving placebo. The most common adverse reaction leading to study withdrawal was impotence (1%).This claim needs references to reliable sources since September 2008

Stop hair loss

Stop Hair Loss

Hair Loss is one part of our life where men and women have always had equal share of difficulty.
Although women mostly suffer from from problems like hair fall,split ends, early greying of hair,short lenght but there are generally spared from a more horrifying truth that most men have to go through is Baldness.

Various remedies, both artificial and natural, have been researched upon and discovered in these many years for this gruesome menace which is haunting the human race.Though over the years herbal and natural treatment to hair fall has seen attracting more patients. the shift is well explained as in matters to skin and hair treatment Ayurveda and Homeopathy has proved to be more fruitful than Common medicinal sciences(read alopathy).

Hence various institutes have come up guarenting you with a complete cure for hair loss.
A few options are listed down below: